RT journal article T1 An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill. A1 García Durán, Alexandra A1 Gutiérrez Vázquez, María Teresa A1 Rodríguez Mejías, Francisco Javier A1 González Molinillo, José María A1 Macías Domínguez, Francisco Antonio A2 Química Orgánica K1 Annona cherimola K1 acetogenins K1 bioactivity K1 acetogenin encapsulation K1 acetogenin formulation K1 acetogenin drug delivery AB Annona cherimola Mill., or the custard apple, is one of the species belonging to the Annonaceae family, is widely used in traditional medicine, and has been reported to be a valuable source of bioactive compounds. A unique class of secondary metabolites derived from this family are Annonaceous acetogenins, lipophilic polyketides considered to be amongst the most potent antitumor compounds. This review provides an overview of the chemical diversity, isolation procedures, bioactivity, modes of application and synthetic derivatives of acetogenins from A. cherimola Mill. PB MDPI SN 1420-3049 YR 2021 FD 2021-05 LK http://hdl.handle.net/10498/25039 UL http://hdl.handle.net/10498/25039 LA eng NO This work was financially supported by the 'Ministerio de Economia y Competitividad' (Project AGL2017-88083-R), Spain. F.J.R.M. thanks Universidad de Cadiz for predoctoral support under grant 2018-009/PU/EPIF-FPI-CT/CP. DS Repositorio Institucional de la Universidad de Cádiz RD 12-nov-2026