RT journal article
T1 Supercritical Impregnation of PLA Filaments with Mango Leaf Extract to Manufacture Functionalized Biomedical Devices by 3D Printing
A1 Rosales, José María
A1 Cejudo Bastante, Cristina
A1 Verano Naranjo, Lidia
A1 Casas Cardoso, Lourdes
A1 Mantell Serrano, Casimiro
A1 Martínez de la Ossa Fernández, Enrique José
A2 Ingeniería Química y Tecnología de Alimentos
K1 supercritical
K1 polylactic acid
K1 impregnation
K1 biomedicine
K1 medical device
K1 mangifera indica
K1 3D printing
K1 additive manufacturing
AB Polylactic Acid (PLA) filaments impregnated with ethanolic mango leaves extract (MLE) with pharmacological properties were obtained by supercritical impregnation. The effects of pressure, temperature and amount of extract on the response variables, i.e., swelling, extract loading and bioactivity of the PLA filaments, were determined. The analysis of the filaments biocapacities revealed that impregnated PLA filaments showed 11.07% antidenaturant capacity and 88.13% antioxidant activity, which after a 9-day incubation shifted to 30.10% and 9.90%, respectively. Subsequently, the same tests were conducted on printed samples. Before their incubation, the printed samples showed 79.09% antioxidant activity and no antidenaturant capacity was detected. However, after their incubation, the antioxidant activity went down to only 2.50%, while the antidenaturant capacity raised up to 23.50%. The persistence of the bioactive properties after printing opens the possibility of using the functionalized PLA filaments as the feed for a three-dimensional (3D) printer.
PB MDPI
YR 2021
FD 2021-07
LK http://hdl.handle.net/10498/25554
UL http://hdl.handle.net/10498/25554
LA eng
NO This work is part of a project granted by the Junta de Andalucia (P18-RT-3272) through its financing by the FEDER funds 2014-2020.
DS Repositorio Institucional de la Universidad de Cádiz
RD 12-nov-2026