RT journal article T1 Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet A1 Pérez Arana, Gonzalo Martín A1 Fernández Vivero, José A1 Camacho Ramírez, Alonso A1 Díaz Gómez, Alfredo Luis A1 Bancalero-de los Reyes, José A1 Ribelles García, Antonio A1 Almorza Gomar, David A1 Carrasco Molinillo, María del Carmen A1 Prada Oliveira, José Arturo A2 Anatomía y Embriología Humana A2 Estadística e Investigación Operativa K1 sleeve gastrectomy K1 roux-en-Y gastric bypass K1 beta-cell K1 alpha-cell K1 epsilon-cell K1 islet K1 trans-differentiation AB Several surgical procedures are performed for the treatment of obesity. A main outcomeof these procedures is the improvement of type 2 diabetes mellitus. Trying to explain this, gastrointestinalhormone levels and their effect on organs involved in carbohydrate metabolism, suchas liver, gut, muscle or fat, have been studied intensively after bariatric surgery. These effects onendocrine-cell populations in the pancreas have been less well studied. We gathered the existingdata on these pancreatic-cell populations after the two most common types of bariatric surgery,the sleeve gastrectomy (SG) and the roux-en-Y gastric bypass (RYGB), with the aim to explain thepathophysiological mechanisms underlying these surgeries and to improve their outcome. PB MDPI SN 2077-0383 YR 2021 FD 2021-09 LK http://hdl.handle.net/10498/25841 UL http://hdl.handle.net/10498/25841 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 11-nov-2026