RT journal article T1 Effects of High-Intensity Interval Training on Inflammatory Biomarkers in Patients with Type 2 Diabetes. A Systematic Review A1 Leiva Valderrama, José Manuel A1 Montes de Oca García, Adrian A1 Opazo Díaz, Edgardo A1 Ponce González, Jesús Gustavo A1 Molina Torres, Guadalupe A1 Velázquez Díaz, Daniel A1 Galán Mercant, Alejandro A2 Didáctica de la Educación FísicaPlástica y Musical A2 Enfermería y Fisioterapia K1 HIIT K1 T2D K1 inflammatory biomarkers AB Background: Due to the prevalence and incidence worldwide of type 2 diabetes, and thesignificant role physical activity plays in these patients, a systematic review has been conductedto find out the effects that high-intensity interval training has on inflammatory biomarkers insubjects with type 2 diabetes. This project aims to determine the effect this training modality hason inflammatory biomarkers, in addition to observing its effects on the values of body compositionand determining if this is a more effective, less effective or equally effective alternative to standardaerobic or resistance training. Methods: A search was conducted in the months of November andDecember 2020 on different databases: Pubmed, WoS and PEDro. A protocol for this systematicreview was registered in PROSPERO (Registration number: CRD42021281186). The studies selectedmet the previously defined inclusion criteria, and the methodological quality of the papers usedwas evaluated according to the Downs and Black Checklist. Results: Out of 46 studies found, sevenwere included. The most relevant data concerning the characteristics of the clinical trials and HIITcharacteristics, the values of body composition and the biomarkers under study were extracted fromeach study. Moreover, the results obtained from the different studies were described. Conclusions:HIIT could have an effect on inflammatory biomarkers. There is likely to be a relationship betweenchanges in inflammatory profile and fat loss. A controlled diet may be a good complement to reducethe inflammatory profile. Further studies are required to determine whether HIIT is a better, worse oran equivalent alternative to medium-intensity aerobic exercise to improve the inflammatory profile PB MDPI SN 1660-4601 YR 2021 FD 2021-12 LK http://hdl.handle.net/10498/26360 UL http://hdl.handle.net/10498/26360 LA eng NO This research and the APC was partial funded by the Erasmus+ Strategic Partnership for Higher Education Program (Key Action 203), grant number 2018-1-PL01-KA203-051055. DS Repositorio Institucional de la Universidad de Cádiz RD 07-nov-2026