RT journal article T1 The Exposome and Immune Health in Times of the COVID-19 Pandemic A1 Morales Rojas, JavierSalvador A1 Valenzuela, Pedro L. A1 Castillo-García, Adrián A1 Butragueño, Javier A1 Jiménez Pavón, David A1 Carrera-Bastos, Pedro A1 Lucia, Alejandro A2 Didáctica de la Educación FísicaPlástica y Musical K1 healthy lifestyle K1 environmental exposure K1 COVID-19 K1 vaccines K1 infectious diseases AB Growing evidence supports the importance of lifestyle and environmental exposures-collectively referred to as the 'exposome'-for ensuring immune health. In this narrative review, we summarize and discuss the effects of the different exposome components (physical activity, body weight management, diet, sun exposure, stress, sleep and circadian rhythms, pollution, smoking, and gut microbiome) on immune function and inflammation, particularly in the context of the current coronavirus disease 2019 (COVID-19) pandemic. We highlight the potential role of 'exposome improvements' in the prevention-or amelioration, once established-of this disease as well as their effect on the response to vaccination. In light of the existing evidence, the promotion of a healthy exposome should be a cornerstone in the prevention and management of the COVID-19 pandemic and other eventual pandemics. PB MDPI SN 2072-6643 YR 2022 FD 2022-01 LK http://hdl.handle.net/10498/26512 UL http://hdl.handle.net/10498/26512 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 10-nov-2026