RT journal article
T1 Blood Pressure Monitoring and Perinatal Outcomes in Normotensive Women with Gestational Diabetes Mellitus
A1 Lara-Barea, Almudena
A1 Sánchez-Lechuga, Begoña
A1 Vidal-Suárez, Álvaro
A1 Arroba Espinosa, Ana Isabel
A1 Bugatto González, Fernando
A1 López Tinoco, Cristina
A2 Materno-Infantil y Radiología
K1 gestational diabetes mellitus
K1 ambulatory blood pressure monitoring
K1 hypertensive disorders of pregnancy
K1 perinatal outcomes
AB Alterations in ambulatory blood pressure detected by monitoring (ABPM) have been associated with perinatal complications in hypertensive pregnant women. Aim: To establish the relationships between the blood pressure (BP) profiles detected by ABPM and adverse perinatal outcomes in normotensive women with gestational diabetes mellitus (GDM). Methods: A prospective study of normotensive women in whom 24 h ABPM was performed at 28-32 weeks of pregnancy. The obstetric and perinatal outcomes were evaluated. Results: Two hundred patients were included. Thirty-seven women with GDM and obesity had significantly higher mean systolic BP (SBP) and nocturnal SBP and diastolic BP (DBP) compared to women with only GDM (n = 86). Nocturnal SBP (OR = 1.077; p = 0.015) and obesity (OR = 1.131; p = 0.035) were risk factors for the development of hypertensive disorders of pregnancy (HDPs). Mothers of newborns with neonatal complications (n = 27) had higher nocturnal SBP (103.8 vs. 100 mmHg; p = 0.047) and DBP (62.7 vs. 59.4; p = 0.016). Women who delivered preterm (n = 10) had higher BP and a non-dipper pattern (p = 0.005). Conclusions: Nocturnal SBP was a predictor of HDPs in normotensive women with obesity or GDM. Alterations in ABPM in these patients were associated with poor obstetric and perinatal outcomes.
PB MDPI
SN 2077-0383
YR 2022
FD 2022-03
LK http://hdl.handle.net/10498/26619
UL http://hdl.handle.net/10498/26619
LA eng
NO This research was funded by the Instituto de Salud Carlos III, grant number "PI16/00370" (co-funded by the European Regional Development Fund, ERDF), and the Biomedical Research and Innovation Institute of Cadiz (INiBICA).
DS Repositorio Institucional de la Universidad de Cádiz
RD 11-nov-2026