RT journal article
T1 Coordination of H2O2 on praseodymia nanorods and its application in sensing cholesterol
A1 Jiang, Lei
A1 Zhong, Junjie
A1 Li, Youxun
A1 Liu, Hanyun
A1 Zhang, Shuyuan
A1 Zhu, Xiudong
A1 Liu, Zhibin
A1 Chen, Yuxue
A1 Fernández García, Susana
A1 Chen, Xiaowei
A2 Ciencia de los Materiales e Ingeniería Metalúrgica y Química Inorgánica
K1 Praseodymium oxide
K1 Pr6O11
K1 Biosensing Cholesterol
K1 Fluorescence detection
AB The advancement of functional nanomaterials has promoted the development of biomarker sensors underpinning promising analytical tools for a range of bioanalytes such as cholesterol. In this work, we established a light-on fluorescent probe for cholesterol in human serum by coordination of H2O2 on the surface of praseodymia nanorods (Pr6O11 NRs). The distinctive interactions of various nucleotides and H2O2 with praseodymia were examined, whereby good fluorescent quenching and recovery capability were observed. A highly sensitive and selective cholesterol detection was achieved in serum samples with a detection limit of 0.1 mu M and recovery of 97.2-101.3%, respectively, due to the high oxygen mobility of praseodymia. The result suggests strong potential for work towards a key probe for a portable clinical test system for cholesterol as well as other H2O2-deriving biomarkers, potentially addressing the ever-increasing demand for the prevention of cardiovascular disease. (C) 2022 Vietnam National University, Hanoi. Published by Elsevier B.V.
PB VIETNAM NATL UNIV
SN 2468-2284
YR 2022
FD 2022-06
LK http://hdl.handle.net/10498/27001
UL http://hdl.handle.net/10498/27001
LA eng
NO This work was supported by the Natural Science Foundation of Shandong Province (Grant ZR2017LB028) , Key R&D Program of Shandong Province (Grant 2018GSF118032) , and Fundamental Research Funds for the Central Universities (Grant 18CX02125A) in China. The project with reference number of ENE2017-82451-C3-2-R from Ministry of Science, Innovation and Universities of Spain is also acknowledged. This work has been co-financed by the 2014-2020 ERDF Operational Programme and by the Department of Economy, Knowledge, Business and University of the Regional Government of Andalusia with reference number of FEDER-UCA18-107316.
DS Repositorio Institucional de la Universidad de Cádiz
RD 11-nov-2026