RT journal article T1 Green Extraction Processes for Complex Samples from Vegetable Matrices Coupled with On-Line Detection System: A Critical Review A1 Maciel-Silva, Francisco W. A1 Lachos-Perez, Daniel A1 Selene Buller, Luz A1 Sganzerla, William G. A1 Pérez García, Montserrat A1 Rostagno, Mauricio Ariel A1 Forster-Carneiro, Tânia A2 Tecnologías del Medio Ambiente K1 sample preparation K1 green extraction techniques K1 on-line coupling K1 fully automated analysis K1 bibliometric analysis AB The detection of analytes in complex organic matrices requires a series of analytical steps to obtain a reliable analysis. Sample preparation can be the most time-consuming, prolonged, and error-prone step, reducing the reliability of the investigation. This review aims to discuss the advantages and limitations of extracting bioactive compounds, sample preparation techniques, automation, and coupling with on-line detection. This review also evaluates all publications on this topic through a longitudinal bibliometric analysis, applying statistical and mathematical methods to analyze the trends, perspectives, and hot topics of this research area. Furthermore, state-of-the-art green extraction techniques for complex samples from vegetable matrices coupled with analysis systems are presented. Among the extraction techniques for liquid samples, solid-phase extraction was the most common for combined systems in the scientific literature. In contrast, for on-line extraction systems applied for solid samples, supercritical fluid extraction, ultrasound-assisted extraction, microwave-assisted extraction, and pressurized liquid extraction were the most frequent green extraction techniques. PB MDPI SN 1420-3049 YR 2022 FD 2022-10 LK http://hdl.handle.net/10498/28691 UL http://hdl.handle.net/10498/28691 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 11-nov-2026