RT journal article
T1 Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.)
A1 Betancor, Mónica B.
A1 Sprague, Matthew
A1 González-Silvera, Daniel
A1 Ortega, Aurelio
A1 Gándara, Fernando de la
A1 Gong, Xu
A1 Napier, Johnathan A.
A1 Tocher, Douglas R.
A1 Mourente Cano, Gabriel
A2 Biología
K1 Atlantic bluefin tuna
K1 GM Camelina
K1 dietary oils
K1 sustainable feeds
K1 hepatic lipid metabolism
AB Recently Camelina sativa, has been genetically modified to produce oils rich in omega-3 (n-3)long-chain polyunsaturated fatty acids (LC-PUFA), EPA (eicosapentaenoic acid) and EPA + DHA(docosahexaenoic acid). The aim of this study was to test the feasibility of using these novel sourcesof de novo EPA and EPA + DHA as substitutes for marine oil in feeds for juvenile Atlantic Bluefintuna (ABT). The results showed the oils were practical sources of n-3 LC-PUFA which could potentially replace fish oil (FO) in feeds for ABT juveniles. Fish fed the test diets (ECO, EPA alone andDCO, EPA + DHA) displayed good growth performance, survival and feed utilisation approaching that of ABT fed the reference diet (MGK) containing marine fish oil with the rank order beingMGK > DCO > ECO. The test diets showed positive effects, upregulating the expression of genesof major nuclear receptors and those of lipid metabolism including digestion, LC-PUFA synthesisand antioxidant pathways. The results indicated that the DCO feed containing both DHA and EPAperformed better than the ECO feed with much lower DHA. However, feeds formulated with boththese oils may still require supplementary DHA to satisfy the high requirement of ABT for thisessential nutrient.
PB MDPI
SN 2410-3888
YR 2022
FD 2022-11-30
LK http://hdl.handle.net/10498/29340
UL http://hdl.handle.net/10498/29340
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 07-nov-2026