RT journal article T1 Longitudinal association of sedentary time and physical activity with pain and quality of life in fibromyalgia A1 Gavilán Carrera, Blanca A1 Delgado Fernández, Manuel A1 Álvarez Gallardo, Inmaculada Concepción A1 Acosta Manzano, Pedro A1 Borges Cosic, Milkana María A1 Estévez López, Fernando A1 Soriano Maldonado, Alberto A1 Carbonell Baeza, Ana A1 Aparicio, Virginia A. A1 Segura Jiménez, Víctor A2 Didáctica de la Educación FísicaPlástica y Musical K1 accelerometry K1 chronic pain K1 GT3X K1 sitting K1 well-being AB Objective: To analyze changes over time and the predictive value of baseline and changes of sedentary time (ST) and physical activity (PA) on pain, disease impact, and health-related quality of life (HRQoL) at 2- and 5-year follow-up in women with fibromyalgia. Methods: This is a longitudinal and exploratory study with three time points. A total of 427 women with fibromyalgia (51.4 ± 7.6 years) were followed after 2 (n = 172) and 5 years (n = 185). ST and PA (light and moderate-to-vigorous [MVPA]) were assessed using triaxial accelerometers. Pain, disease impact, and HRQoL were measured using: pressure pain threshold, the pain subscale of the revised fibromyalgia impact questionnaire (FIQR), the bodily pain subscale of the 36-item short-form health survey (SF-36), a visual analog scale (VAS), the FIQR, and the SF-36 physical and mental components. Results: Over 5 years, pressure pain threshold, ST, light PA, and MVPA variables were worsened, while FIQR and SF-36 variables were improved (Cohen's d < 0.1–0.3). Baseline ST or light PA were not associated with future outcomes, whereas greater MVPA at baseline was associated with better SF-36 bodily pain at 5-year follow-up (β = 0.13). Reducing ST and increasing light PA were associated with better bodily pain (β = −0.16 and 0.17, respectively) and SF-36 physical component (β = −0.20 and 0.17, respectively) at 5-year follow-up. Increasing MVPA was associated with less pain (pressure pain threshold, VAS, and FIQR-pain) and better SF-36 physical component at 2- and 5-year follow-up (β's from −0.20 to 0.21). Conclusions: Objectively measured variables slightly worsened over years, while for self-reported outcomes there was a trend for improvement. Reductions in ST and increases in light PA and MVPA were associated with better HRQoL at 5-year follow-up, and increases in MVPA were additionally associated with better pain and HRQoL at 2-year follow-up. PB Wiley SN 0905-7188 YR 2022 FD 2022-11-03 LK http://hdl.handle.net/10498/29708 UL http://hdl.handle.net/10498/29708 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 07-nov-2026