RT journal article T1 The Val158Met Polymorphism in 8-Year-Old Boys and Girls Moderates the Influence of Parenting Styles on Proactive Aggression: Testing the Sensitivity to the Environment A1 del Puerto-Golzarri, Nora A1 Azurmendi, Aitziber A1 Muñoz Sánchez, José Manuel A1 Carreras de Alba, María Rosario A1 Pascual-Sagastizábal, Eider A2 Psicología K1 aggressive behavior K1 parenting styles K1 COMT K1 differential susceptibility K1 diathesis-stress AB The aim of the study was to explore the possible vulnerability (diathesis-stress), susceptibility (differential susceptibility), or vantage (vantage sensitivity) properties of COMT gen Val158Met polymorphism to adverse and favorable parenting styles from both parents in relation to children’s reactive and proactive aggressive behavior. Within 279 eight-year-old children (125 girls and 154 boys) from Spain, reactive and proactive aggressive behavior was measured through the “Reactive and Proactive Questionnaire” (RPQ). Saliva samples were collected to genotype for the COMT Val158Met polymorphism via real-time PCR. Finally, parenting styles were assessed using the “Parenting Styles and Dimensions Questionnaire” (PSDQ). The results revealed that for boys, the Met allele was a vulnerability factor for proactive aggression in response to low-authoritative parenting from the father. For girls, it was the Val allele, the vulnerability variable to the high authoritarian style of the father, and the susceptibility factor to the authoritative style of the mother over proactive aggression. The results are discussed, considering possible sex differences. Our results indicate that the COMT Val158Met polymorphism is a biological variable that confers greater sensitivity to the environment. PB MDPI SN 2076-3425 YR 2023 FD 2023-10-26 LK http://hdl.handle.net/10498/29857 UL http://hdl.handle.net/10498/29857 LA eng NO This research was funded by the Spanish Ministry of Economy and Competitiveness (PSI2016-75462-P), the UPV/EHU GIU18/103 Project Grants, and the Basque Country Government (grant number: PRE_2018_1_0111) DS Repositorio Institucional de la Universidad de Cádiz RD 08-nov-2026