RT journal article T1 Preparation and Phytotoxicity Evaluation of 11,13-Dehydro seco-Guaianolides A1 Chinchilla Salcedo, Nuria A1 Santana, Alejandro A1 Varela Montoya, Rosa María A1 Fronczek, Frank R A1 González Molinillo, José María A1 Macías Domínguez, Francisco Antonio A2 Química Orgánica AB 11,13-Dehydro seco-guaianolides, a particular type of sesquiterpene lactones, were synthesized from the commercially available α-santonin (11) using a facile strategy involving a high-yielding photochemical reaction. Natural products 10 and 17 from Artemisia gorgonum were synthesized in good yields.Specifically, compound 10 was obtained in five steps with an overall yield of 17%. The sesquiterpene lactones were tested in the etiolated wheat coleoptile bioassay, and the most active compounds were assayed on standard target species. Guaianolide 13 showed the highest phytotoxic activities when compared with the known herbicide Logran. SN 1520-6025 YR 2019 FD 2019 LK http://hdl.handle.net/10498/29916 UL http://hdl.handle.net/10498/29916 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 12-nov-2026