RT journal article T1 Modelling and Optimization of Simultaneous Saccharification and Fermentation of Agro-Food Residues A1 Caro Pina, Ildefonso A1 Marzo Gago, Cristina A1 Díaz Sánchez, Ana Belén A1 Blandino Garrido, Ana María A2 Ingeniería Química y Tecnología de Alimentos AB In terms of productivity, bioethanol production from agri-food residues can be improved by carrying out simultaneously the two involved stages (enzyme hydrolysis and alcohol fermentation). This is because the shorter the process duration, the higher the overall productivity achieved. In this work, two kinetic models previously developed by the authors have been combined to obtain a general kinetic model for the simultaneous saccharification and fermentation of lignocellulosic materials. The validity of the combined model has been tested using three different agri-food residues: wheat straw, rice husks and exhausted sugar beet pulp. Later, the model has been used to calculate productivity under many different conditions and to optimize the industrial process. After this study, it is concluded that some important operating variables, such as the enzyme dose and the inoculum strength, must be well coupled to obtain the maximal yield from residues. Thus, the overall productivity obtained in the laboratory experiments was under 5 mg of ethanol per gram of solid waste and per hour. However, the simulations in the optimal operating conditions predict productivities up to double that. PB Elsevier YR 2024 FD 2024-01 LK http://hdl.handle.net/10498/29952 UL http://hdl.handle.net/10498/29952 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 06-nov-2026