RT journal article
T1 Enhancing Anthocyanin Extraction fromWine Lees: A Comprehensive Ultrasound-Assisted Optimization Study
A1 Umsza-Guez, Marcelo A.
A1 Vázquez Espinosa, Mercedes
A1 Chinchilla Salcedo, Nuria
A1 Aliaño González, María José
A1 Oliveira de Souza, Carolina
A1 Ayena, Kodjovi
A1 Fernández Barbero, Gerardo
A1 Carrera Fernández, Ceferino Adrián
A2 Química Analítica
A2 Química Orgánica
K1 wine lees
K1 by-products
K1 ultrasound-assisted extraction
K1 anthocyanins
K1 antioxidant activity
K1 Box–Behnken design
K1 circular economy
AB Wine lees, an important by-product of the wine industry, pose a major environmentalproblem due to the enormous quantities of solid–liquid waste that are discarded annually withoutdefined applications. In this study, the optimization of a method based on a Box–Behnken designwith surface response has been carried out to obtain extracts with high anthocyanin content andpotent antioxidant activity. Six variables have been considered: %EtOH, temperature, amplitude,cycle, pH, and ratio. The developed method exhibited important repeatability properties andintermediate precision, with less than 5% CV being achieved. Furthermore, these novel methodswere successfully applied to diverse wine lees samples sourced from Cabernet Sauvignon andSyrah varieties (Vitis vinifera), resulting in extracts enriched with significant anthocyanin contentand noteworthy antioxidant activity. Additionally, this study evaluated the influence of grapevariety, fermentation type (alcoholic or malolactic), and sample treatment on anthocyanin content andantioxidant activity, providing valuable insights for further research and application in various sectors.The potential applications of these high-quality extracts extend beyond the winemaking industry,holding promise for fields like medicine, pharmaceuticals, and nutraceuticals, thus promoting acircular economy and mitigating environmental contamination.
PB MDPI
SN 2076-3921
YR 2023
FD 2023
LK http://hdl.handle.net/10498/29999
UL http://hdl.handle.net/10498/29999
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 08-nov-2026