RT journal article
T1 Optimisation of an ultrasound-assisted extraction method for the simultaneous determination of phenolics in rice grains
A1 Setyaningsih, Widiastuti
A1 Sapruto, Irfan E.
A1 Carrera Fernández, Ceferino Adrián
A1 Palma Lovillo, Miguel
A2 Química Analítica
K1 Ultrasound-Assisted extraction
K1 Phenolics
K1 UPLC-PDA
K1 Rice grains
AB Fifteen phenolic compounds were determined in rice grains by ultrasound assisted extraction and ultra-performance liquid chromatography with photodiode array detection. Primarily, an UAE method has been developed and validated for the extraction of phenolics from rice grains. For the optimization, a Box–Behnken Design based on six factors including extraction temperature (10–70 °C), solvent composition (0–50% methanol in water), cycle (0.2–0.7 s−1), ultrasound amplitude (30–70%), and solvent to sample ratio (2.5:1 to 5:1) was employed. Multi-response optimization (MRO) was performed to develop a simultaneous extraction method of 15 phenolics. The optimal UAE conditions were: extraction temperature 45 °C, time 25 min, cycle 0.4 s−1, ultrasoundamplitude 47%, solvent composition 80% methanol in water at pH 4.25, and sample to solvent ratio1:5. Linearity, LODs, LOQs, precision and recovery were determined. In addition, the method was successfullyapplied to analyse a number of rice samples with different varieties
PB Elsevier
SN 1873-7072
YR 2019
FD 2019
LK http://hdl.handle.net/10498/30063
UL http://hdl.handle.net/10498/30063
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 12-nov-2026