RT journal article T1 Metabolism of antifungal thiochroman-4-ones by Trichoderma viride and Botrytis cinerea A1 Pinedo Rivilla, Cristina A1 González Collado, Isidro A1 Aleu Casatejada, Josefina A2 Química Orgánica AB Biotransformation of 6-methylthiochroman-4-one (1) and 6-chlorothiochroman-4-one (2) was performedusing Trichoderma viride in order to obtain new derivativeswith antifungal properties against the phytopathogen Botrytiscinerea. Two thiochromanone derivatives are described for thefirst time. Antifungal activity of these compounds was testedagainst two different strains of Botrytis cinerea; 1 and 2 gave100% inhibition of Bc2100 at 100−250 μg/mL, and 3 gave amaximal inhibition of 96% of BcUCA992 at 200 μg/mL. Thedetoxification mechanism of 1 and 2 by B. cinerea was alsoinvestigated. PB AMER CHEMICAL SOC SN 1520-6025 YR 2018 FD 2018 LK http://hdl.handle.net/10498/30245 UL http://hdl.handle.net/10498/30245 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 12-nov-2026