RT journal article
T1 Pain in Neuropsychiatry: Insights From Animal Models
A1 Bravo García, Lidia
A1 Llorca Torralba, Meritxell
A1 Suárez-Pereira, Irene
A1 Berrocoso Domínguez, Esther María
A2 Neurociencias
A2 Psicología
AB Pain is the most common symptom reported in clinical practice, meaning that it is associated with manypathologies as either the origin or a consequence of other illnesses. Furthermore, pain is a complex emotional and sensorial experience, as the correspondence between pain and body damage varies considerably. While these issues are widely acknowledged in clinical pain research, until recently they have not been extensively considered when exploring animal models, important tools for understanding pain pathophysiology. Interestingly, chronic pain is currently considered a risk factor to suffer psychiatric disorders, mainly stress-related disorders like anxiety and depression. Conversely, pain appears to be altered in many psychiatric disorders, such as depression, anxiety and schizophrenia. Thus, pain and psychiatric disorders have been linked in epidemiological and clinical terms, although the neurobiological mechanisms involved in this pathological bidirectional relationshipremain unclear. Here we review the evidence obtained from animal models about the co-morbidity ofpain and psychiatric disorders, placing special emphasis on the different dimensions of pain.
PB Elsevier
SN 1873-7528
YR 2020
FD 2020-08
LK http://hdl.handle.net/10498/30265
UL http://hdl.handle.net/10498/30265
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 10-may-2026