RT journal article T1 Regular Exercise Improved Fatigue and Musculoskeletal Pain in Young Adult Psoriatic Patients without Psoriatic Arthritis A1 Díaz Ordóñez, Antonio Jesús A1 Rosety Rodríguez, Miguel Ángel A1 Armario Hita, José Carlos A1 Bandez Ruiz, Manuel Jesús A1 García Gómez, Natalia A1 Sánchez Sánchez, Eduardo A1 Diaz, Jara A1 Castejon-Riber, Cristina A1 Bernardi, M. A1 Rosety Rodríguez, Manuel A1 Ordóñez Muñoz, Francisco Javier A1 Rosety Rodríguez, Ignacio A2 Anatomía y Embriología Humana K1 fatigue K1 musculoskeletal health K1 nutrition K1 physical activity K1 psoriasis AB Fatigue and musculoskeletal pain are also frequent in patients with psoriasis (PsO) without arthritis (PsA). The current study aimed to assess the impact of an intervention program based on aerobic training to reduce fatigue and musculoskeletal pain in patients with PsO without PsA. A total of 118 male patients with PsO volunteered in the current interventional study and were randomly allocated to the experimental (n = 59) or control group (n = 59). The intervention consisted of a 16-week aerobic training program on a treadmill, three sessions per week, consisting of a warm-up, 35-50 min treadmill exercise (increasing 5 min/4 weeks) at a work intensity of 50-65% of peak heart-rate (increasing 5%/4 weeks), and cooling-down. The functional assessment of chronic illness therapy fatigue scale (FACIT-Fatigue), health assessment questionnaire disability index (HAQ-DI), and visual analog scale (VAS) were compared pre and post intervention. Nutritional intake, maximal aerobic power, lipid profile, serum markers of muscle damage, and body composition were also assessed. When compared to baseline, FACIT-Fatigue, HAQ-DI, and VAS scores were significantly improved without increasing markers of muscle damage. Fat mass percentage, lipid profile, and maximal oxygen consumption were also improved. In conclusion, a 16-week aerobic training program at moderate intensity was safe, well tolerated, and effective in psoriatic patients without PsA. Long-term follow-up studies are required to examine whether these promising results may improve clinical outcomes. PB MDPI SN 2072-6643 YR 2023 FD 2023 LK http://hdl.handle.net/10498/30461 UL http://hdl.handle.net/10498/30461 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 21-sep-2026