RT journal article
T1 Safety Study of Transcranial Static Magnetic Field Stimulation (tSMS) of the Human Cortex
A1 Oliviero, A
A1 Carrasco-López, MC
A1 Campolo, M
A1 Perez-Borrego, Y
A1 Soto Leon, Vanesa
A1 González Rosa, Javier Jesús
A1 Higuero, AM
A1 Strange, BA
A1 Abad-Rodriguez, J
A1 Foffani, G
A2 Psicología
K1 NIBS
K1 Neuron-specific enolase
K1 Repetitive transcranial magnetic stimulation (rTMS)
K1 S100
K1 Safety
K1 Transcranial static magnetic field stimulation (tSMS)
AB Background: Transcranial static magnetic field stimulation (tSMS) in humans reduces cortical excitability.Objective: The objective of this study was to determine if prolonged tSMS (2 h) could be delivered safely in humans. Safety limits for this technique have not been described.Methods: tSMS was applied for 2 h with a cylindric magnet on the occiput of 17 healthy subjects. We assessed tSMS-related safety aspects at tissue level by measuring levels of neuron-specific enolase (NSE, a marker of neuronal damage) and S100 (a marker of glial reactivity and damage). We also included an evaluation of cognitive side effects by using a battery of visuomotor and cognitive tests.Results: tSMS did not induce any significant increase in NSE or S100. No cognitive alteration was detected.Conclusions: Our data indicate that the application of tSMS is safe in healthy human subjects, at least within these parameters.
PB ELSEVIER SCIENCE BV
SN 1935-861X
YR 2015
FD 2015-05-01
LK http://hdl.handle.net/10498/30688
UL http://hdl.handle.net/10498/30688
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 12-nov-2026