RT journal article T1 Social determinants of multimorbidity patterns: A systematic review A1 Álvarez Gálvez, Javier A1 Ortega Martín, María Esther A1 Carretero Bravo, Jesús Ángel A1 Pérez Muñoz, Celia A1 Sanz Suarez-Lledo, Víctor José A1 Ramos Fiol, Begoña A2 BiomedicinaBiotecnología y Salud Pública A2 Economía General A2 Ingeniería Mecánica y Diseño Industrial K1 behavioral determinants K1 chronic conditions K1 chronicity K1 comorbidity K1 multimorbidity K1 ocial determinants AB Social determinants of multimorbidity are poorly understood in clinical practice. This review aims to characterize the different multimorbidity patterns described in the literature while identifying the social and behavioral determinants that may affect their emergence and subsequent evolution. We searched PubMed, Embase, Scopus, Web of Science, Ovid MEDLINE, CINAHL Complete, PsycINFO and Google Scholar. In total, 97 studies were chosen from the 48,044 identified. Cardiometabolic, musculoskeletal, mental, and respiratory patterns were the most prevalent. Cardiometabolic multimorbidity profiles were common among men with low socioeconomic status, while musculoskeletal, mental and complex patterns were found to be more prevalent among women. Alcohol consumption and smoking increased the risk of multimorbidity, especially in men. While the association of multimorbidity with lower socioeconomic status is evident, patterns of mild multimorbidity, mental and respiratory related to middle and high socioeconomic status are also observed. The findings of the present review point to the need for further studies addressing the impact of multimorbidity and its social determinants in population groups where this problem remains invisible (e.g., women, children, adolescents and young adults, ethnic groups, disabled population, older people living alone and/or with few social relations), as well as further work with more heterogeneous samples (i.e., not only focusing on older people) and using more robust methodologies for better classification and subsequent understanding of multimorbidity patterns. Besides, more studies focusing on the social determinants of multimorbidity and its inequalities are urgently needed in low- and middle-income countries, where this problem is currently understudied. PB Frontiers Media SN 2296-2565 YR 2023 FD 2023-03-27 LK http://hdl.handle.net/10498/31183 UL http://hdl.handle.net/10498/31183 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 06-nov-2026