RT journal article T1 Health-Promoting Additives Supplemented in Inert Microdiets for Whiteleg Shrimp (Penaeus vannamei) Post-Larvae: Effects on Growth, Survival, and Health Status A1 Barreto, André A1 Peixoto, Diogo A1 Fajardo Quiñones, Carlos A1 Pinto, Wilson A1 Rocha, Rui J. M. A1 Conceição, Luís E. C. A1 Costas, Benjamín A2 BiomedicinaBiotecnología y Salud Pública K1 antioxidants K1 dietary additives K1 health status K1 immunostimulants K1 microdiets K1 Penaeus vannamei K1 post larvae K1 whiteleg shrimp AB Dietary additives have the potential to stimulate the whiteleg shrimp immune system, but information is scarce on their use in diets for larval/post-larval stages. The potential beneficial effects of vitamins C and E, β-glucans, taurine, and methionine were evaluated. Four experimental microdiets were tested: a positive control diet (PC); the PC with decreased levels of vitamin C and E as negative control (NC); the PC with increased taurine and methionine levels (T + M); and the PC supplemented with β-glucans (BG). No changes in growth performance and survival were observed. However, post-larvae shrimp fed the NC had lower relative expressions of pen-3 than those fed the PC, suggesting that lower levels of vitamins C and E may impact the shrimp immune status. Lipid peroxidation levels dropped significantly in the BG compared to the PC, indicating that β-glucans improved the post-larvae antioxidant mechanisms. Furthermore, when compared with the NC diet, PL fed with BG showed significant increases in tGSH levels and in the relative expression of crus and pen-3, suggesting a synergistic effect between vitamins C and E and β-glucans. Amongst the additives tested, β-glucans seems to be the most promising even when compared to a high-quality control diet PB MDPI SN 2076-2615 YR 2023 FD 2023-02-17 LK http://hdl.handle.net/10498/31201 UL http://hdl.handle.net/10498/31201 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 07-nov-2026