RT journal article T1 Personal care products: an emerging threat to the marine bivalve Ruditapes philippinarum A1 Pintado Herrera, Marina Guadalupe A1 Aguirre-Martínez, Gabriela V. A1 Martín Díaz, María Laura A1 Blasco, Julián A1 Lara Martín, Pablo Antonio A1 Sendra, Marta A2 Química Física K1 Personal care product K1 Bioconcentration K1 Clam K1 PCP post-exposure K1 Effects K1 Biomarkers AB In the last few decades, there has been a growing interest in understanding the behavior of personal care products (PCPs)in the aquatic environment. In this regard, the aim of this study is to estimate the accumulation and effects of four PCPswithin the clam Ruditapes philippinarum. The PCPs selected were triclosan, OTNE, benzophenone-3, and octocrylene. Aprogressive uptake was observed and maximum concentrations in tissues were reached at the end of the exposure phase,up to levels of 0.68 μg g−1, 24 μg g−1, 0.81 μg g−1, and 1.52 μg g−1 for OTNE, BP-3, OC, and TCS, respectively. After thePCP post-exposure period, the removal percentages were higher than 65%. The estimated logarithm bioconcentration factorranged from 3.34 to 2.93, in concordance with the lipophobicity of each substance. No lethal effects were found althoughsignificant changes were observed for ethoxyresorufin O-demethylase activity, glutathione S-transferase activity, lipid peroxidation,and DNA damage. PB Springer YR 2024 FD 2024-02-05 LK http://hdl.handle.net/10498/31216 UL http://hdl.handle.net/10498/31216 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 21-sep-2026