RT journal article T1 A deep sift convolutional neural networks for total brain volume estimation from 3D ultrasound images A1 Jafrasteh, Bahram A1 Lubián López, Simón A1 Benavente Fernández, Isabel A2 Materno-Infantil y Radiología K1 Computer K1 Neural Networks K1 Longitudinal Studies K1 Premature K1 Infant K1 Infant, Newborn K1 Three-Dimensional K1 Imaging K1 Computer-Assisted K1 Image Processing K1 Humans K1 Brain AB Preterm infants are a highly vulnerable population. The total brain volume (TBV) of these infants can be accurately estimated by brain ultrasound (US) imaging which enables a longitudinal study of early brain growth during Neonatal Intensive Care (NICU) admission. Automatic estimation of TBV from 3D images increases the diagnosis speed and evades the necessity for an expert to manually segment 3D images, which is a sophisticated and time consuming task. We develop a deep-learning approach to estimate TBV from 3D ultrasound images. It benefits from deep convolutional neural networks (CNN) with dilated residual connections and an additional layer, inspired by the fuzzy c-Means (FCM), to further separate the features into different regions, i.e. sift layer. Therefore, we call this method deep-sift convolutional neural networks (DSCNN). The proposed method is validated against three state-of-the-art methods including AlexNet-3D, ResNet-3D, and VGG-3D, for TBV estimation using two datasets acquired from two different ultrasound devices. The results highlight a strong correlation between the predictions and the observed TBV values. The regression activation maps are used to interpret DSCNN, allowing TBV estimation by exploring those pixels that are more consistent and plausible from an anatomical standpoint. Therefore, it can be used for direct estimation of TBV from 3D images without needing further image segmentation. PB Elsevier SN 1872-7565 YR 2023 FD 2023 LK http://hdl.handle.net/10498/31577 UL http://hdl.handle.net/10498/31577 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 10-nov-2026