RT journal article
T1 Prevalence of Depression and Related Factors among Patients with Chronic Disease during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis
A1 García Lara, Rubén  A.
A1 Suleiman Martos, Nora
A1 Membrive Jiménez, María J.
A1 García Morales, Victoria
A1 Quesada Caballero, Miguel
A1 Guisado Requena, Isabel M.
A1 Gómez Urquiza, José L.
A2 BiomedicinaBiotecnología y Salud Pública
K1 chronic disease
K1 COVID-19
K1 depression
K1 prevalence
K1 related factors
AB The management of chronic diseases in the midst of the COVID-19 pandemic is especially challenging, and reducing potential psychological harm is essential. This review aims to determine the prevalence of depression during the COVID-19 pandemic in patients with chronic disease, and to characterize the impacts of related factors. A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The meta-analysis was performed using StatsDirect software. The review identified 33 articles with a total of 50,905 patients with chronic diseases. Four meta-analyses were performed to estimate the prevalence of depression. In diabetic patients, the prevalence ranged from 17% (95% CI = 7–31) (PHQ-9) to 33% (95% CI = 16–51) (PHQ-8); in obese patients, the prevalence was 48% (95% CI = 26–71); and in hypertensive patients, the prevalence was 18% (95% CI = 13–24). The factors significantly associated with depression were female sex, being single, deterioration in the clinical parameters of diabetes, a decrease in self-care behavior, reduced physical activity and sleep time and fear of contagion. The COVID-19 pandemic has significantly increased levels of depression among persons with chronic disease. Pandemics and other emergency events have a major impact on mental health, so early psychological interventions and health management policies are needed to reinforce chronic patients’ physical and mental health.
PB MDPI
SN 2075-4418
YR 2022
FD 2022-12-08
LK http://hdl.handle.net/10498/31595
UL http://hdl.handle.net/10498/31595
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 08-nov-2026