RT journal article
T1 Sex-Specific Relationships of Physical Activity and Sedentary Behaviour with Oxidative Stress and Inflammatory Markers in Young Adults
A1 Corral Pérez, Juan
A1 Alcalá, Martín
A1 Velázquez Díaz, Daniel
A1 Perez Bey, Alejandro
A1 Vázquez Sánchez, María Ángeles
A1 Calderón Domínguez, María
A1 Casals Vázquez, Cristina
A1 Ponce González, Jesús Gustavo
A2 BiomedicinaBiotecnología y Salud Pública
A2 Didáctica de la Educación FísicaPlástica y Musical
K1 accelerometry; antioxidants; gender; inflammation; sedentarism
K1 accelerometry
K1 antioxidants
K1 gender
K1 inflammation
K1 sedentarism
AB This study aims to analyse sex-specific associations of physical activity and sedentary behaviour with oxidative stress and inflammatory markers in a young-adult population. Sixty participants (21 women, 22.63 ± 4.62 years old) wore a hip accelerometer for 7 consecutive days to estimate their physical activity and sedentarism. Oxidative stress (catalase, superoxide dismutase, glutathione peroxidase, glutathione, malondialdehyde, and advanced oxidation protein products) and inflammatory (tumour necrosis factor-alpha and interleukin-6) markers were measured. Student t-tests and single linear regressions were applied. The women presented higher catalase activity and glutathione concentrations, and lower levels of advanced protein-oxidation products, tumour necrosis factor-alpha, and interleukin-6 than the men (p < 0.05). In the men, longer sedentary time was associated with lower catalase activity (β = −0.315, p = 0.04), and longer sedentary breaks and higher physical-activity expenditures were associated with malondialdehyde (β = −0.308, p = 0.04). Vigorous physical activity was related to inflammatory markers in the women (tumour necrosis factor-alpha, β = 0.437, p = 0.02) and men (interleukin−6, β = 0.528, p < 0.01). In conclusion, the women presented a better redox and inflammatory status than the men; however, oxidative-stress markers were associated with physical activity and sedentary behaviours only in the men. In light of this, women could have better protection against the deleterious effect of sedentarism but a worse adaptation to daily physical activity.
PB MDPI
SN 1661-7827
YR 2023
FD 2023-01-04
LK http://hdl.handle.net/10498/31682
UL http://hdl.handle.net/10498/31682
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 08-nov-2026