RT journal article
T1 Ten Issues to Update in Nosocomial or Hospital-Acquired Pneumonia: An Expert Review
A1 Cande, F.J.
A1 Salavert, M.
A1 Estella García, Ángel
A1 Ferrer, M.
A1 Ferrer, R.
A1 Gamazo, J.J.
A1 García-Vidal, C.
A1 del Castillo, J.G.
A1 González-Ramallo, V.J.
A1 Gordo, F.
A1 Mirón-Rubio, M.
A1 Pérez-Pallarés, J.
A1 Pitart, C.
A1 del Pozo, J.L.
A1 Ramírez, P.
A1 Rascado, P.
A1 Reyes, S.
A1 Ruiz-Garbajosa, P.
A1 Suberviola, B.
A1 Vidal, P.
A2 Medicina
K1 Nosocomial pneumonia
K1 Healthcare-associated pneumonia
K1 Etiology
K1 Epidemiology
K1 Diagnosis stewardship
K1 Radiologic findings
K1 Management
K1 Readmission
K1 Therapeutic failure
K1 Rescue
K1 Hospital at home
K1 Prevention
K1 Vaccination
AB Nosocomial pneumonia, or hospital-acquired pneumonia (HAP), and ventilator-associated pneumonia (VAP) are important health problems worldwide, with both being associated with substantial morbidity and mortality. HAP is currently the main cause of death from nosocomial infection in critically ill patients. Although guidelines for the approach to this infection model are widely implemented in international health systems and clinical teams, information continually emerges that generates debate or requires updating in its management. This scientific manuscript, written by a multidisciplinary team of specialists, reviews the most important issues in the approach to this important infectious respiratory syndrome, and it updates various topics, such as a renewed etiological perspective for updating the use of new molecular platforms or imaging techniques, including the microbiological diagnostic stewardship in different clinical settings and using appropriate rapid techniques on invasive respiratory specimens. It also reviews both Intensive Care Unit admission criteria and those of clinical stability to discharge, as well as those of therapeutic failure and rescue treatment options. An update on antibiotic therapy in the context of bacterial multiresistance, in aerosol inhaled treatment options, oxygen therapy, or ventilatory support, is presented. It also analyzes the out-of-hospital management of nosocomial pneumonia requiring complete antibiotic therapy externally on an outpatient basis, as well as the main factors for readmission and an approach to management in the emergency department. Finally, the main strategies for prevention and prophylactic measures, many of them still controversial, on fragile and vulnerable hosts are reviewed.
PB Multidisciplinary Digital Publishing Institute (MDPI)
SN 2077-0383
YR 2023
FD 2023
LK http://hdl.handle.net/10498/31716
UL http://hdl.handle.net/10498/31716
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 13-nov-2026