RT journal article
T1 Biphasic Bioceramic Obtained from Byproducts of Sugar Beet Processing for Use in Bioactive Coatings and Bone Fillings
A1 Suffo Pino, Miguel
A1 Cauqui López, Miguel Ángel
A1 Pérez Muñoz, Celia
A1 Goma Jiménez, Daniel
A1 Fernández Delgado, Natalia
A1 Herrera Collado, Miriam
A2 Ciencia de los Materiales e Ingeniería Metalúrgica y Química Inorgánica
A2 Ingeniería Mecánica y Diseño Industrial
K1 Biphasic bioceramic
K1 Hydroxyapatite
K1 Carbocal®
K1 Viability
K1 Bioactive coating
K1 Bone cement
AB This study focuses on developing hydroxyapatite synthesized from a CaCO3-rich byproduct of sugar beet processing called Carbocal® using a hydrothermal reactor. The purpose of thisbiomaterial is to enhance the osteoinductivity of implantable surfaces and serve as a bone filler,providing a sustainable and economically more affordable alternative. This research involved compositional analysis and micro- and macrostructural physicochemical characterization, complementedwith bioactivity and live/dead assays. The biphasic nature of the Carbocal®-derived sample wassignificant within the context of the bioactivity concept previously proposed in the literature. Thebioactivity of the biomaterial was demonstrated through a viability test, where the cell growth wasnearly equivalent to that of the positive control. For comparison purposes, the same tests wereconducted with two additional samples: hydroxyapatite obtained from CaCO3 and commercialhydroxyapatite. The resulting product of this process is biocompatible and possesses propertiessimilar to natural hydroxyapatite. Consequently, this biomaterial shows potential as a scaffold intissue engineering and as an adhesive filler to promote bone regeneration within the context of thecircular bioeconomy in the geographical area proposed.
PB Multidisciplinary Digital Publishing Institute (MDPI)
SN 2079-4983
YR 2023
FD 2023
LK http://hdl.handle.net/10498/31755
UL http://hdl.handle.net/10498/31755
LA eng
NO Junta de Andalucía
DS Repositorio Institucional de la Universidad de Cádiz
RD 11-nov-2026