RT journal article
T1 Extraction of Bioactive Compounds from Prestonia mollis Leaves and Their Impregnation into Polylactic Acid Using High-Pressure Technologies: Potential for Biomedical Application
A1 Burgos Briones, Gabriel Alfonso
A1 Verano Naranjo, Lidia
A1 Cejudo Bastante, Cristina
A1 Dueñas-Rivadeneira, A.A.
A1 Mantell Serrano, Casimiro
A1 Casas Cardoso, Lourdes
A2 Ingeniería Química y Tecnología de Alimentos
K1 Prestonia mollis
K1 Pressurized liquid extraction
K1 Enhanced solvent extraction
K1 Antioxidant activity
AB Enhanced solvent extraction (ESE) and pressurized liquid extraction (PLE) have been usedfor the first time to obtain antioxidant compounds from Prestonia mollis leaves. The effects of pressure(100–250 bar), temperature (55–75 ◦C) and the composition of the extraction solvent (ethanol, waterand hydroalcoholic mixtures) were evaluated according to multilevel factorial designs. PLE providedthe largest extraction yields compared to ESE, as well as a greater impact of the operating conditionsstudied. The highest total phenolic content was obtained when using a hydroalcoholic mixture(CO2/ethanol/water 50/25/25) through ESE at 100 bar and 75 ◦C. The antioxidant capacity of thisextract is related to higher concentration levels of the identified flavonoids: Quercetin 3-O-xylosylrutinoside, Kaempferol 3-(2G-apiosylrobinobioside) and Kaempferol 40-glucoside 7-rhamnoside. Thisextract was tested for the supercritical impregnation of polylactic acid (PLA), which is a polymerwidely used in the biomedical industry. The influence of pressure (100–400 bar), temperature(35–55 ◦C), amount of extract (3–6 mL) and impregnation time (1–2 h) have been evaluated. The bestresults were obtained by impregnating 3 mL of extract at 100 bar and 55 ◦C for 2 h, achieving 10%inhibition with DPPH methods. The extract presented a potentially suitable impregnation of PLA forbiomedical applications.
PB Multidisciplinary Digital Publishing Institute (MDPI)
SN 2076-3921
YR 2023
FD 2023
LK http://hdl.handle.net/10498/31787
UL http://hdl.handle.net/10498/31787
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 11-nov-2026