RT journal article T1 Risk and Protective Factors for Frailty in Pre-Frail and Frail Older Adults A1 Corral Pérez, Juan A1 Ávila Cabeza de Vaca, Laura A1 González Mariscal, Andrea María A1 Espinar Toledo, Milagrosa A1 Ponce González, Jesús Gustavo A1 Casals Vázquez, Cristina A1 Vázquez Sánchez, María Ángeles A2 Didáctica de la Educación FísicaPlástica y Musical K1 accelerometry K1 ageing K1 dependency K1 physical activity K1 physical function K1 strength AB This study aims to evaluate the differences in body composition, physical function, and physical activity between pre-frail/frail older adults and to detect risk and protective factors against frailty and physical frailty. Fried’s criteria for frailty and physical frailty using the short-performance physical battery (SPPB) were measured in 179 older participants (75.3 ± 6.4 years old). Body weight, height, and waist, arm, and leg circumferences were obtained as body composition variables. Daily accelerometer outcomes (physical activity and inactivity) were obtained. Pre-frail participants showed overall better physical function and spent more time in physical activity and less time in long inactivity periods than frail participants (p < 0.05). Risk frailty factors were higher waist perimeter (Odds Ratio [OR]: 1.032, 95%CI: 1.003–1.062), low leg performance (OR: 1.025, 95%CI: 1.008–1.043), and inactivity periods longer than 30 min (OR: 1.002, 95%CI: 1.000–1.005). Protective factors were standing balance (OR: 0.908, 95%CI: 0.831–0.992) and SPPB score (OR: 0.908, 95%CI: 0.831–0.992) for frailty, handgrip strength (OR: 0.902, 95%CI: 0.844–0.964) for physical frailty, and light (OR: 0.986, 95%CI: 0.976–0.996) and moderate-to-vigorous (OR: 0.983, 95%CI: 0.972–0.996) physical activity for both. Our findings suggest that handgrip strength, balance, and physical activity are protective frailty factors and can be monitored in pre-frail older adults. Moreover, poor lower body performance and long inactivity periods are frailty risk factors, which highlights their importance in frailty assessment. PB MDPI SN 1661-7827 YR 2023 FD 2023-02-10 LK http://hdl.handle.net/10498/31791 UL http://hdl.handle.net/10498/31791 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 12-nov-2026