RT journal article
T1 Measurement Properties of Self-Report Questionnaires for Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis of Commonly Used Instruments
A1 Sánchez Andrades, María José
A1 Viñolo Gil, María Jesús
A1 Casuso Holgado, María Jesús
A1 Barón López, Javier
A1 Rodríguez Huguet, Manuel
A1 Martín Valero, Rocío
A2 Enfermería y Fisioterapia
K1 amyotrophic lateral sclerosis
K1 design questionnaire
K1 patient reported outcome measures
K1 quality of life
K1 systematic review
K1 validation studies
AB (1) Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. There is no evidence on the analysis of the measurement instruments available to assess quality of life in these patients, following the consensus-based standards for the selection of health measurement instruments (COSMIN) checklist; (2) Methods: A systematic review was performed in PubMed, Embase, PEDro, Web of Science and Cochrane. The psychometric properties of the questionnaires were determined by using the COSMIN checklist. Two searches were carried out. This systematic review was registered in PROSPERO (CRD42021249005); (3) Results: There were four published articles that analysed the measurement properties in patients with ALS for the following scales: Amyotrophic Lateral Sclerosis Assessment Questionnaire 40, Amyotrophic Lateral Sclerosis-Specific Quality of Life Questionnaire, Short Form 36 Healthy Survey, Epworth Sleepiness Scale and Sickness Impact Profile. Another five scales also met the inclusion criteria: ALS-Depression-Inventory, State Trait Anxiety-Inventory, World Health Organization Quality of Life, Schedule for the Evaluation of Individual Quality of Life, Amyotrophic Lateral Sclerosis Assessment Questionnaire 5. Most Patient Reported Outcome Measures (PROMs) present a low-quality synthesis of evidence. It was observed an excellent pooled reliability of 0.92 (95% Confidence Interval: 0.83–0.96, I2 = 87.3%) for four dimensions for questionnaires ALSAQ-40. (4) Conclusions: There is little evidence on generic instruments. Future studies are necessary to develop new tools.
PB MDPI
SN 1661-7827
YR 2023
FD 2023-02-14
LK http://hdl.handle.net/10498/31792
UL http://hdl.handle.net/10498/31792
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 09-nov-2026