RT journal article T1 Use of Iontophoresis with Corticosteroid in Carpal Tunnel Syndrome: Systematic Review and Meta-Analysis A1 Martín Vega, Francisco Javier A1 Viñolo Gil, María Jesús A1 González Medina, Gloria A1 Rodríguez Huguet, Manuel A1 Carmona Barrientos, Inés María A1 García Muñoz, Cristina A2 Enfermería y Fisioterapia K1 carpal tunnel syndrome K1 corticosteroids K1 iontophoresis K1 meta-analysis K1 systematic review AB Background: Carpal tunnel syndrome is a neuropathy that affects the median nerve. The aim of this review is to synthesize the evidence and perform a meta-analysis on the effects of iontophoresis in people with carpal tunnel syndrome. Methods: The search was carried out using PubMed, Web of Science, Scopus, CINHAL Complete, Physiotherapy Evidence Database, and SciELO. The methodological quality was evaluated using PEDro. A standardized or mean difference meta-analysis (Hedge’s g) using a random-effects model was calculated. Results: Seven randomized clinical trials using iontophoresis for electrophysiological, pain, and functional outcomes were included. The mean of PEDro was 7/10. No statistical differences were obtained for the median sensory nerve conduction velocity (SMD = −0.89; p = 0.27) or latency (SMD = −0.04; p = 0.81), motor nerve conduction velocity (SMD = −0.04; p = 0.88) or latency (SMD = −0.01; p = 0.78), pain intensity (MD = 0.34; p = 0.59), handgrip strength (MD = −0.97; p = 0.09), or pinch strength (SMD = −2.05; p = 0.06). Iontophoresis only seemed to be superior in sensory amplitude (SMD = 0.53; p = 0.01). Conclusions: Iontophoresis did not obtain an enhanced improvement compared to other interventions, but no clear recommendations could be made due to the limited number of included studies and the heterogeneity found in the assessment and intervention protocols. Further research is needed to draw sound conclusions. PB MDPI SN 1661-7827 YR 2023 FD 2023-02-28 LK http://hdl.handle.net/10498/31805 UL http://hdl.handle.net/10498/31805 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 08-nov-2026