RT journal article
T1 Cocaine and depressive disorders: When standard clinical diagnosis is insufficient
A1 Alías-Ferri, María
A1 García-Marchena, Nuria
A1 Mestre-Pintó, Joan
A1 Araos, Pedro
A1 Vergara Moragues, Esperanza
A1 Fonseca, Francina
A1 González Saiz, Francisco Manuel
A1 Rodríguez de Fonseca, Fernando
A1 Torrens, Marta
A1 NEURODEP, Group
A2 Neurociencias
A2 Psicología
K1 Dual diagnosis
K1 cocaine use disorder
K1 cocaine-related disorders
K1 depressive disorder
K1 induced depression
AB Background: Cocaine use is a growing global health problem and patients with cocaine use disorders (CUD) present several complications, including high rates of major depression. These subjects present two types of major depressive disorder (MDD): primary major depressive disorder (P-MDD) and cocaine-induced major depressive disorder (CI-MDD). To improve treatment, it is necessary to distinguish between both types. The aim of this study was to assess the differences in depressive symptomatology criteria (P-MDD vs CI-MDD) in CUD patients.Methods: Secondary data analysis was carried out with a cross-sectional sample of 160 patients presenting CUD and MDD. Clinical assessment was performed using the Psychiatric Research Interview for Substance and Mental Disorders (PRISM). A differential diagnosis was obtained between P-MDD and CI-MDD.Results: Men represented 80% of the sample, the mean age was 38.61 years, and 64.5% had elementary studies. CI-MDD diagnosis (61.3%) was more frequent than P-MDD (38.7%). There was a younger age of CUD onset in CI-MDD patients. In addition, 79.4% of the patients had another substance use disorder diagnosis. The criterion "Changes in weight or appetite" was more prevalent (57.1%) in P-MDD group.Conclusions: We found differences in the criterion "Changes in weight or appetite". Further research is needed in this field to establish a differential diagnosis and thus provide better treatment for CUD patients.
SN 0214-4840
YR 2021
FD 2021
LK http://hdl.handle.net/10498/33106
UL http://hdl.handle.net/10498/33106
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 10-may-2026