RT journal article T1 Multivariate Base Rates of Low Score on Neuropsychological Tests of Individuals with Coca Paste Use Disorder A1 Vergara Moragues, Esperanza A1 Acosta Barreto, María Rocío A1 Rivera, Diego A1 Santiago-Ramajo, Sandra A1 González Saiz, Francisco Manuel A1 Arango Lasprilla, Juan Carlos A2 Psicología A2 Neurociencias K1 Coca paste K1 Substance abuse K1 Neuropsychology K1 Diagnosis K1 Psychometrics AB Objective: The aim of this study was to determine the prevalence of low scores on eight commonly used neuropsychological tests to evaluate learning and memory, language and executive functions in individuals with coca paste use disorders (CPUD) and to identify the differences with respect to a group of healthy nonconsuming subjects (HCs). Methods: A total of 162 Colombian adults with CPUD and a group of 162 Colombian adult HCs participated in this study. Eight tests (eighteen test scores) were grouped into three categories: learning and memory, language, and executive functions. Each participant was categorized based on the number of low scoring tests in specific percentile cut-off groups (25th, 16th, 10th, 5th, and 2nd). Results: In the learning and memory domain, 89.5% of individuals with CPUD and 55.6% of HCs scored below the 25th percentile on at least one of the five test scores, in the language domain, 80.7% of individuals with CPUD and 58% of HCs and in the executive function domain, 92% of individuals with CPUD and 67.3% of HCs. Having two or more scores below the 10th percentile or 10 or more at the 5th percentile shows an optimal cut-off for determining the sensitivity and specificity for discriminating between the two groups. Conclusions: The individuals with CPUD had a higher percentage of low scores than the HCs in the domains of learning and memory, language, and executive function. It is important for clinicians to be aware of low scores in individuals with CPUD to avoid false-positive diagnoses. YR 2023 FD 2023 LK http://hdl.handle.net/10498/33111 UL http://hdl.handle.net/10498/33111 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 10-may-2026