RT journal article T1 Generation of Spherical Microparticles of Moringa Leaves through a Supercritical Antisolvent Extraction Process A1 Montes Herrera, Antonio A1 Valor López, Diego A1 Pereyra López, Clara María A1 Martínez de la Ossa Fernández, Enrique José A2 Ingeniería Química y Tecnología de Alimentos K1 supercritical antisolvent K1 Moringa leaves K1 antioxidants K1 extraction K1 particle size AB The objective of this work was evaluation of the supercritical antisolvent extraction (SAE)process to generate microparticles with antioxidant activity from Moringa leaves. A biodegradablepolymer was used as an inductor of particle precipitation. An ethanolic extract of 25 mg/mL was usedin the SAE process, during which the influences of pressure (100–200 bar), temperature (35–55 C)and extract–polymer ratio (0.11–0.33) on particle size and antioxidant activity were evaluated. Anextract flow rate of 3 mL/min, a supercritical CO2 (scCO2) flow rate of 30 g CO2/min and a nozzlediameter of 100 m were kept constant. The identification of several compounds of Moringa leaves,namely, coumaric acid and quercetin 3D glucoside, were determined with ultra-performance liquidchromatography coupled with mass spectrometry. The antioxidant activity of the extract and the precipitateswas measured with 2,2-Diphenyl-1-picrylhydrazyl. Spherical microparticles with diametersin the range of 2–5 m were obtained, with moderate antioxidant activity. PB MDPI SN 2673-4079 YR 2023 FD 2023 LK http://hdl.handle.net/10498/33549 UL http://hdl.handle.net/10498/33549 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 11-nov-2026