RT journal article
T1 Sleep Behaviors and the Shape of Subcortical Brain Structures in Children with Overweight/Obesity: A Cross-Sectional Study
A1 Cadenas Sánchez, Cristina
A1 Migueles, Jairo H.
A1 Torres López, Lucía V.
A1 Verdejo Román, Juan
A1 Jiménez Pavón, David
A1 Hillman, C.H.
A1 Catena, A
A1 Ortega, F.B.
A2 Didáctica de la Educación FísicaPlástica y Musical
K1 Brain shapes
K1 Grey matter
K1 Obesity
K1 Sleep
K1 Actigraphy
AB Objectives: To examine the relationship between sleep and subcortical brain structures using a shape analysis approach. Methods: A total of 98 children with overweight/obesity (10.0 ± 1.1 y, 59 boys) were included in the cross-sectional analyses. Sleep behaviors (i.e., wake time, sleep onset time, total time in bed, total sleep time, sleep efficiency, and wakening after sleep onset) were estimated with wrist-worn accelerometers. The shape of the subcortical brain structures was acquired by magnetic resonance imaging. A partial correlation permutation approach was used to examine the relationship between sleep behaviors and brain shapes. Results: Among all the sleep variables studied, only total time in bed was significantly related to pallidum and putamen structure, such that those children who spent more time in bed had greater expansions in the right and left pallidum (211–751 voxels, all p’s <0.04) and right putamen (1783 voxels, p = 0.03). Conclusions: These findings suggest that more time in bed was related to expansions on two subcortical brain regions in children with overweight/obesity.
PB Springer
SN 0973-7693
YR 2024
FD 2024
LK http://hdl.handle.net/10498/33702
UL http://hdl.handle.net/10498/33702
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 12-nov-2026