RT journal article
T1 Dereplication of Bioactive Agave Saponin Fractions: The Hidden Saponins
A1 Simonet Morales, Ana María
A1 García Durán, Alexandra
A1 Macías Domínguez, Francisco Antonio
A2 Química Orgánica
K1 Agave macroacantha
K1 A. colorata
K1 A. parryi
K1 A. parrasana
K1 dereplication
K1 steroidal saponin
K1 coloratoside
K1 HMAI
K1 bioherbicide
K1 apiose
AB The good phytotoxicity and selectivity against weeds versus tomato or cress make saponin-rich fractions from Agave macroacantha, A. colorata, A. parryi, and A. parrasana attractive candidates as bioherbicides. The saponin contents have only previously been reported for A. macroacantha, and as a consequence, simultaneous dereplication has been performed on saponin-rich fractions from the other plants by mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. This strategy enables the identification of a total of 26 saponins, 14 of which have been described previously and 12 of which are proposed as new saponins. They include isomers and a new sugar chain with a β-d-apiofuranose unit. The method is corroborated by the isolation of eight dereplicated saponins from A. colorata.
PB American Chemical Society
SN 0021-8561
YR 2024
FD 2024
LK http://hdl.handle.net/10498/33739
UL http://hdl.handle.net/10498/33739
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 06-nov-2026