RT journal article T1 Effects of lipid-based nutrient supplements v. micronutrient powders on nutritional and developmental outcomes among Peruvian infants A1 Matías, Susana L. A1 Vargas Vásquez, Alejandro A1 Bado Pérez, Ricardo A1 Alcázar Valdivia, Lorena A1 Aquino Vivanco, Oscar A1 Rodriguez Martín, Amelia A1 Novalbos Ruiz, José Pedro A2 BiomedicinaBiotecnología y Salud Pública K1 Lipid-based nutrient supplement K1 Micronutrient powder K1 Anaemia K1 Stunting K1 Child development K1 Problem solving K1 Peru AB Objective To determine the effects of lipid-based nutrient supplements (LNS) on children's Hb, linear growth and development, compared with supplementation with micronutrient powder (MNP). Design The study was a two-arm parallel-group randomized controlled trial, where participants received either LNS or MNP for daily consumption during 6 months. Supplements were delivered by staff at government-run health centres. Hb, anthropometric, motor development, language development and problem-solving indicators were measured by trained research assistants when children were 12 months of age. Setting The study was conducted in five rural districts in the Province of Ambo in the Department of Huánuco, Peru. Subjects We enrolled 6-month-old children (n 422) at nineteen health centres. Results Children who received LNS had a higher mean Hb concentration and lower odds of anaemia than those who received MNP. No significant differences in height-for-age, weight-for-height or weight-for-age Z-score, or stunting and underweight prevalence, were observed. Provision of LNS was associated with a higher pre-verbal language (gestures) score, but such effect lost significance after adjustment for covariates. Children in the LNS group had higher problem-solving task scores and increased odds of achieving this cognitive task than children in the MNP group. No significant differences were observed on receptive language or gross motor development. Conclusions LNS between 6 and 12 months of age increased Hb concentration, reduced anaemia and improved cognitive development in children, but showed no effects on anthropometric indicators, motor or language development. PB Cambridge University Press SN 1475-2727 YR 2017 FD 2017 LK http://hdl.handle.net/10498/33825 UL http://hdl.handle.net/10498/33825 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 07-nov-2026