RT journal article
T1 Health-Promoting Properties of Natural Flavonol Glycosides Isolated from Staphylea pinnata L.
A1 Paolillo, Ida
A1 Roscigno, Giuseppina
A1 Innangi, M.
A1 García Zorrilla, Jesús
A1 Petraglia, Gianmarco
A2 Química Orgánica
K1 antiaging ingredients
K1 antimicrobial
K1 antioxidants
K1 flavonoids
K1 flavonol glycosides
K1 Staphylea
AB Staphylea, also called bladdernuts, is a genus of plants belonging to the family Staphyleaceae, widespread in tropical or temperate climates of America, Europe, and the Far East. Staphylea spp. produce bioactive metabolites with antioxidant properties, including polyphenols which have not been completely investigated for their phytotherapeutic potential, even though they have a long history of use for food. Here, we report the isolation of six flavonol glycosides from the hydroalcoholic extract of aerial parts of Staphylea pinnata L., collected in Italy, using a solid-phase extraction technique. They were identified using spectroscopic, spectrometric, and optical methods as three quercetin and three isorhamnetin glycosides. Among the flavonol glycosides isolated, isoquercetin and quercetin malonyl glucoside showed powerful antioxidant, antimicrobial, and wound healing promoting activity and thus are valuable as antiaging ingredients for cosmeceutical applications and for therapeutic applications in skin wound repair.
PB Multidisciplinary Digital Publishing Institute (MDPI)
SN 1422-0067
YR 2024
FD 2024
LK http://hdl.handle.net/10498/33834
UL http://hdl.handle.net/10498/33834
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 10-nov-2026