RT journal article
T1 Microwave-Assisted One-Pot Telescoped Synthesis of 2-Amino-1,3-thiazoles, Selenazoles, Imidazo[1,2-a]pyridines, and Other Heterocycles from Alcohols
A1 Macías Benítez, Pablo
A1 Sierra Padilla, Alfonso
A1 Guerra Martínez, Francisco Miguel
A1 Moreno Dorado, Francisco Javier
A2 Química Analítica
A2 Química Orgánica
K1 Alcohols
K1 Column chromatography
K1 Heterocyclic compounds
K1 Irradiation
K1 Mixtures
AB Primary and secondary alcohols have been con-verted into 2-amino-1,3-thiazoles under microwave irradiation,employing trichloroisocyanuric acid (TCCA) as a dual oxidant andchlorine source, TEMPO as a co-oxidant, and thiourea. Secondaryalcohols underwent a single-stage, one-pot conversion process,while primary alcohols required a two-stage, one-pot procedure.Both transformations were completed within minutes (25−45min). The versatility of this protocol extends to the synthesis ofother heterocycles, including 1,3-selenazoles, 2-aminoimidazoles,imidazo[1,2-a]pyridines, quinoxalines, and hydrazino thiazoles byreplacing thiourea with the appropriate surrogates
PB ACS Publications
SN 1520-6904
YR 2024
FD 2024
LK http://hdl.handle.net/10498/33838
UL http://hdl.handle.net/10498/33838
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 21-sep-2026