RT journal article T1 Profiling of phenolic natural products in the seagrass zostera noltei by UPLC-MS A1 Manck, Lauren A1 Quintana, Ester A1 Brun Murillo, Fernando Guillermo A1 Hernández Carrero, Ignacio A1 Ortega Agüera, María Jesús A1 Zubía Mendoza, Eva A2 Biología A2 Química Orgánica K1 Seagrasses K1 Zostera noltei K1 Phenolic natural products K1 Rosmarinic acid K1 Flavonoid sulfates K1 UPLC-MS analysis AB Seagrasses are marine plants that play important ecological functions in coastal ecosystems. The species Zostera noltei is widely distributed along the European coasts thriving in a variety of environmental conditions. In this study, the phenolic natural products of Z. noltei have been analyzed quantitatively by using UPLC-MS. Plants from the Natural Park of the Bay of Cadiz (Spain) were shown to contain rosmarinic acid (1) and the flavonoids apigenin-7-O-glucoside (2), luteolin-7-sulfate (7), apigenin-7-sulfate (8), diosmetin-7-sulfate (9), and acacetin-7-sulfate (10). The analysis by UPLC-MS of extracts allowed the quantification of all the compounds and evidenced the intraspecific variations in the profile of natural products among plants collected at different dates and locations within the Bay. The flavonoids 2, and 7-10 were present in all the analyzed samples with a total flavonoid content in the range 12.8-72.3 mg/g dry wt, while rosmarinic acid (1) was only present in some samples, reaching up to 19.6 mg/g dry wt. A distinctive feature of plants from the Bay of Cadiz is the common presence of apigenin-7-sulfate (8) as major flavonoid, differing from plants from other regions whose major flavonoid is diosmetin-7-sulfate (9). PB Natural Product Incorporation SN 1555-9475 YR 2017 FD 2017 LK http://hdl.handle.net/10498/33859 UL http://hdl.handle.net/10498/33859 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 10-nov-2026