RT journal article
T1 Patulin degradation by the biocontrol yeast Sporobolomyces sp. Is an inducible process
A1 Ianiri, Giuseppe
A1 Pinedo Rivilla, Cristina
A1 Fratianni, Alessandra
A1 Panfili, Gianfranco
A1 Castoria, Raffaello
A2 Química Orgánica
K1 Sporobolomyces sp. IAM13481
K1 microbial patulin degradation
K1 ascladiol
K1 desoxypatulinic acid
AB Patulin is a mycotoxin produced by Penicillium expansum and a common contaminantof pome fruits and their derived products worldwide. It is considered to be mutagenic,genotoxic, immunotoxic, teratogenic and cytotoxic, and the development of strategies to reducethis contamination is an active field of research. We previously reported that Sporobolomyces sp.is able to degrade patulin and convert it into the breakdown products desoxypatulinic acid andascladiol, both of which were found to be less toxic than patulin. The specific aim of this study wasthe evaluation of the triggering of the mechanisms involved in patulin resistance and degradation bySporobolomyces sp. Cells pre-incubated in the presence of a low patulin concentration showed a higherresistance to patulin toxicity and a faster kinetics of degradation. Similarly, patulin degradationwas faster when crude intracellular protein extracts of Sporobolomyces sp. were prepared from cellspre-treated with the mycotoxin, indicating the induction of the mechanisms involved in the resistanceand degradation of the mycotoxin by Sporobolomyces sp. This study contributes to the understandingof the mechanisms of patulin resistance and degradation by Sporobolomyces sp., which is an essentialprerequisite for developing an industrial approach aiming at the production of patulin-free products.
PB MDPI
SN 2072-6651
YR 2017
FD 2017
LK http://hdl.handle.net/10498/34027
UL http://hdl.handle.net/10498/34027
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 10-nov-2026