RT journal article T1 Central obesity measurements predict metabolic syndrome in a retrospective cohort study of postmenopausal women. A1 Rosety Rodríguez, Manuel A1 Fornieles González, Gabriel A1 Rosety Rodríguez, Ignacio A1 Díaz Ordóñez, Antonio Jesús A1 Rosety Rodríguez, Miguel Ángel A1 Camacho, Alejandra A1 Rodríguez Pareja, María Antonia A1 Tejerina, A. A1 Ordóñez Muñoz, Francisco Javier A2 Anatomía y Embriología Humana A2 Didáctica de la Educación FísicaPlástica y Musical A2 Medicina K1 Down syndrome K1 central adiposity K1 intellectual disability K1 metabolic syndrome K1 women K1 DXA AB Introduction: The various diagnostic classifications in the literature concur as regards the important role of abdominal obesity in the onset and progression of metabolic syndrome. Accordingly, this study was aimed at clarifying whether central obesity measurements assessed by dual X-ray absorptiometry (DXA) may predict metabolic syndrome in Spanish postmenopausal women.Material and methods: This historical cohort study included a total of 1326 postmenopausal women aged > 45 years old who had routinely undergone DXA to measure their bone mineral density between January 2006 and January 2011. The regions of interest (ROI) envisaged in our study by using DXA were the lumbar regions L1-L4 and L4-L5. At the same time, they underwent a complete medical examination including personal medical history assessment, biochemical blood analysis, blood pressure measurement and anthropometrical evaluation. Metabolic syndrome was diagnosed attending to the criteria established by National Cholesterol Education Program Adult Treatment Panel III (NECP-ATP-III).Results: During the observation period, 537 women, representing 40.5% of the total studied, met the diagnostic criteria for metabolic syndrome. L1-L4 and L4-L5 abdominal fat mass determinations were associated with the development of metabolic syndrome in all regression models tested, showing an increasing gradient from the lowest to highest quintile.Conclusion: Central adiposity measurements assessed by DXA, especially L1-L4 region of interest, could be considered a powerful predictor of metabolic syndrome in postmenopausal women. PB AULA MEDICA SN 0212-1611 YR 2013 FD 2013-11-01 LK http://hdl.handle.net/10498/34711 UL http://hdl.handle.net/10498/34711 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 07-nov-2026