RT journal article
T1 Antioxidant and Anti-inflammatory Meroterpenoids from the Brown Alga Cystoseira usneoides
A1 Reyes Jiménez, Carolina de los
A1 Zbakh, Hanna
A1 Motilva, Virginia
A1 Zubía Mendoza, Eva
A2 Química Orgánica
AB A chemical study of the alga Cystoseira usneoides has led to the isolation of six new meroterpenoids, cystodiones A−F (1−6), together with six known related compounds (7−12). The structures of the new metabolites have been established by spectroscopic techniques. In antioxidant assays all of the tested meroterpenes, and in particular cystodiones A (1) and B (2), 6-cis-amentadione-1′-methyl ether (7), and amentadione-1′ methyl ether (8), exhibited strong radical-scavenging activity. In antiinflammatory assays, usneoidone Z (11) and its corresponding 6E isomer (12) showed significant activity as inhibitors of the production of the proinflammatory cytokine TNF-α in LPS-stimulated THP-1 human macrophages.
PB ACS
SN 0163-3864
YR 2013
FD 2013-03-04
LK http://hdl.handle.net/10498/34727
UL http://hdl.handle.net/10498/34727
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 06-nov-2026