RT journal article
T1 Supercritical CO2 impregnation of silica microparticles with quercetin
A1 García Casas, Ignacio
A1 Crampon, Christelle
A1 Montes Herrera, Antonio
A1 Pereyra López, Clara María
A1 Martínez de la Ossa Fernández, Enrique José
A1 Badens, Elisabeth
A2 Ingeniería Química y Tecnología de Alimentos
AB Supercritical carbon dioxide has been used to develop two methods for the impregnation of porous silica beads with a natural antioxidant, quercetin. These methods involved batch and semi-continuous supercritical impregnations. The first experiments performed in batch mode helped to understand the influence of pressure, temperature, duration, and the presence of a co-solvent on the impregnation efficiency. A co-solvent was added due to the low solubility of quercetin in supercritical CO2 under the operating conditions studied. In the range of temperatures and pressures studied, the best operating conditions, i.e., those that led to the highest quantity of quercetin impregnated (300 �����g of quercetin per g of silica), were 10 MPa and 323 K with ethanol as co-solvent for 2 hours. These operating conditions, highlighted through the batch mode experiments, were subsequently applied to the semi-continuous process. This approach provided an impregnation ratio of 240 ug of quercetin per g of silica
PB ELSEVIER
SN 0896-8446
YR 2019
FD 2019-01
LK http://hdl.handle.net/10498/35075
UL http://hdl.handle.net/10498/35075
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 21-sep-2026