RT journal article T1 Automatic CDR Estimation for Early Glaucoma Diagnosis A1 Fernández Granero, Miguel Ángel A1 Sarmiento Vega, Auxiliadora A1 Sánchez Morillo, Daniel A1 Jiménez Carmona, Soledad A1 Alemany Márquez, Pedro María A1 Fondón García, Irene A2 Ingeniería en AutomáticaElectrónica, Arquitectura y Redes de Computadores AB Glaucoma is a degenerative disease that constitutes the second cause of blindness in developed countries. Although it cannot be cured, its progression can be prevented through early diagnosis. In this paper, we propose a new algorithm for automatic glaucoma diagnosis based on retinal colour images. We focus on capturing the inherent colour changes of optic disc (OD) and cup borders by computing several colour derivatives in CIE L∗a∗b∗ colour space with CIE94 colour distance. In addition, we consider spatial information retaining these colour derivatives and the original CIE L∗a∗b∗ values of the pixel and adding other characteristics such as its distance to the OD centre. The proposed strategy is robust due to a simple structure that does not need neither initial segmentation nor removal of the vascular tree or detection of vessel bends. The method has been extensively validated with two datasets (one public and one private), each one comprising 60 images of high variability of appearances. Achieved class-wise-averaged accuracy of 95.02% and 81.19% demonstrates that this automated approach could support physicians in the diagnosis of glaucoma in its early stage, and therefore, it could be seen as an opportunity for developing low-cost solutions for mass screening programs. PB Wiley SN 2040-2309 YR 2017 FD 2017 LK http://hdl.handle.net/10498/35239 UL http://hdl.handle.net/10498/35239 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 22-sep-2026