RT journal article
T1 Effects of early-life amino acids supplementation on fish responses to a thermal challenge
A1 Navarro-Guillén, C.
A1 Jerez Cepa, Ismael
A1 Lopes, A.
A1 Mancera Romero, Juan Miguel
A1 Engrola, S.
A2 Biología
K1 Amino acids
K1 Early nutritional programming
K1 Fish thermal adaptation
K1 Water temperature
K1 Zebrafish larvae
AB Nutritional programming is a promising concept for promoting metabolic adaptation of fish to challenging conditions, suchas the increase in water temperature. The present work evaluates in ovo arginine or glutamine supplementation as enhanc-ers of zebrafish metabolic or absorptive capacity, respectively, at optimum (28 ºC) and challenging temperatures (32 ºC)in the long-term. Growth performance, free amino acids profile, methylation index and the activity levels of digestive andintermediary metabolism enzymes were analysed to assess the metabolic plasticity induced by an early nutritional interven-tion. Temperature affected fish larvae growth performance. At the end of the experimental period 28 ºC-fish showed higherdry weight than 32 ºC-fish. The effects of the early supplementation were reflected in the larval free amino acids profile atthe end of the experiment. Higher methylation potential was observed in the ARG-fish. In ovo amino acid supplementationmodulated the metabolic response in zebrafish larvae, however, the magnitude of this effect differed according to the aminoacid and the temperature. Overall, arginine supplementation enhanced carbohydrates metabolism at 32 ºC. In conclusion, thepresent work suggests that in ovo arginine supplementation may promote a better adaptive response to higher temperatures.
PB Springer Science and Business Media Deutschland GmbH
SN 0174-1578
YR 2024
FD 2024
LK http://hdl.handle.net/10498/35516
UL http://hdl.handle.net/10498/35516
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 08-nov-2026