RT journal article
T1 Assessment of Solvent Extraction using Sonication to Recover Tryptophan from Kappaphycus alvarezii(Doty) Doty ex Silva: Experimental and Modelling
A1 Galih Perkasa Putra, Venansius
A1 Chaniago, Weni
A1 Izmi, Nuzulia
A1 Mutiarahma, Selma
A1 Adi Kurnia, Kiki
A1 Palma Lovillo, Miguel
A1 Setyaningsih, Widiastuti
A2 Química Analítica
K1 COSMOS-RS
K1 Multilevel factorial design
K1 Ultrasound-assisted extraction
K1 Polarity
K1 Affinity
K1 Ethanol
K1 HPLC-DAD
AB The application of Kappaphycus alvarezii in the food system has attracted researchers due to its bioactive compounds, including tryptophan. The present study was conducted to extract tryptophan from K. alvarezii with the aid of sonication. A reduced multilevel factorial design was conducted to evaluate the effect of solvent, ultrasound power, duty-pulse cycle, time and temperature on the recovery of tryptophan. Analysis of variance suggested that the type of solvent and combination setting of power and duty-pulse cycle significantly influenced the extraction (p < 0.05). In contrast, extraction time and temperature did not alter the extraction (p > 0.05). The optimum was using ethanol, ultrasound power 80 %, pulse duty-cycle 0.8 s–1, extraction time 10 min, and temperature 25 °C and tryptophan concentration was 56.41 ± 2.42 mg L–1. Subsequently, a COnducto-like Screening MOdel for Real Solvent (COSMO-RS) was performed to clarify the impact of solvent affinity and polarity on the tryptophan extraction from K. alvarezii.
PB Trends in Sciences
SN 2774-0226
YR 2024
FD 2024-08-20
LK http://hdl.handle.net/10498/35550
UL http://hdl.handle.net/10498/35550
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 10-nov-2026