RT journal article
T1 A narrative review of inherited arrhythmogenic syndromes in young population: Role of genetic diagnosis in exercise recommendations
A1 Sarquella Brugada, Georgia
A1 Martínez  Barrios, Estefanía
A1 Cesar, Sergi
A1 Toro Cebada, Rocío
A1 Cruzalegui, José
A1 Greco, Andrea
A1 Díez Escuté, Nuria
A1 Cerralbo, Patricia
A1 Chipa, Fredy
A1 Arbelo, Elena
A1 Diez López, Carles
A1 Grazioli, Gonzalo
A1 Balderrábano, Norma
A1 Campuzano, Oscar
A2 Medicina
AB Sudden cardiac death is a rare but socially devastating event, especially if occurs in young people. Usually, this unexpected lethal event occurs during or just after exercise. One of the leading causes of sudden cardiac death is inherited arrhythmogenic syndromes, a group of genetic entities characterised by incomplete penetrance and variable expressivity. Exercise can be the trigger for malignant arrhythmias and even syncope in population with a genetic predisposition, being sudden cardiac death as the first symptom. Due to genetic origin, family members must be clinically assessed and genetically analysed after diagnosis or suspected diagnosis of a cardiac channelopathy. Early identification and adoption of personalised preventive measures is crucial to reduce risk of arrhythmias and avoid new lethal episodes. Despite exercise being recommended by the global population due to its beneficial effects on health, particular recommendations for these patients should be adopted considering the sport practised, level of demand, age, gender, arrhythmogenic syndrome diagnosed but also genetic diagnosis. Our review focuses on the role of genetic background in sudden cardiac death during exercise in child and young population.
PB BMJ Publishing Group
SN 2055-7647
YR 2024
FD 2024
LK http://hdl.handle.net/10498/35655
UL http://hdl.handle.net/10498/35655
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 10-may-2026