RT journal article
T1 Ginger Phytotoxicity: Potential Efficacy of Extracts, Metabolites and Derivatives for Weed Control
A1 García Zorrilla, Jesús
A1 Rial Cumbrera, Carlos
A1 Martínez González, Miriam Inmaculada
A1 González Molinillo, José María
A1 Macías Domínguez, Francisco Antonio
A1 Varela Montoya, Rosa María
A2 Química Orgánica
K1 bioassays
K1 gingerol
K1 natural products
K1 phenolic compounds
K1 shogaol
K1 structure-activity relationships
K1 weed management
AB The negative implications for weeds encourage the finding of novel sources of phytotoxic agents for sustainable management. While traditional herbicides are effective, especially at large scales, the environmental impact and proliferation of resistant biotypes present major challenges that natural sources could mitigate. In this study, the potential of ginger metabolites as phytotoxic agents has been investigated for the first time. Root extracts, prepared via various extraction techniques, showed phytotoxicity in wheat (Triticum aestivum L. cv. Burgos) coleoptile bioassays at 800–100 ppm, and the most active extract (prepared by sonication with ethyl acetate) was purified by chromatographic methods, yielding seven compounds: five phenolic metabolites with gingerol and shogaol structures, β-sitosterol, and linoleic acid. Some of the major phenolic metabolites, especially [6]-shogaol and [6]-gingerol, exerted phytotoxicity on wheat coleoptiles, Plantago lanceolata and Portulaca oleracea (broadleaf dicotyledon weeds). This promoted the study of a collection of derivatives, revealing that the 5-methoxy, oxime, and acetylated derivatives of [6]-shogaol and [6]-gingerol had interesting phytotoxicities, providing clues for improving the stability of the isolated structures. Ginger roots have been demonstrated to be a promising source of bioactive metabolites for weed control, offering novel materials with potential for the development of agrochemicals based on natural products.
PB Multidisciplinary Digital Publishing Institute (MDPI)
SN 2073-4395
YR 2024
FD 2024
LK http://hdl.handle.net/10498/35839
UL http://hdl.handle.net/10498/35839
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 06-nov-2026