RT journal article T1 Self-Medication Practice and Associated Factors Among Health Professionals in Spain A1 Cotobal Calvo, E.M. A1 Mata Pérez, Concepción A1 Bocchino, Anna A1 Gilart Cantizano, Ester A1 Gutierrez Baena, Belén A1 Palazón-Fernández, José Luis A2 Enfermería y Fisioterapia K1 attitude K1 health professionals K1 perceived efficacy K1 self-medication AB (1) Background: Self-medication, defined as the use of medications without professional supervision, is a common practice that presents both potential benefits and significant risks. This study analyzes the prevalence, patterns, and determinants of self-medication among health professionals in Spain. (2) Methods: A cross-sectional descriptive design was employed with 438 health professionals, predominantly women (81.1%), with a median age of 42 years. The majority of the healthcare workers were nurses (45%). (3) Results: The results revealed a high prevalence of self-medication (59.4%). Analgesics and anti-inflammatory drugs were the most commonly used. Age and professional knowledge emerged as significant factors influencing this behavior. The main reasons for self-medication included the mildness of symptoms, easy access to medications, and previous successful experiences. Digital sources, especially websites, were the most consulted. Confidence in artificial intelligence tools as a clinical resource was moderate, with 18% of participants consulting AI tools, a rate comparable to the 19.5% for scientific databases. Logistic regression analysis identified age, knowledge of recommended doses, and perceived efficacy as significant predictors, while concern about risks acted as a protective factor. (4) Conclusions: This study highlights the need for educational interventions aimed at promoting responsible self-medication practices and mitigating associated risks among healthcare professionals. PB Multidisciplinary Digital Publishing Institute (MDPI) SN 2039-4403 YR 2025 FD 2025 LK http://hdl.handle.net/10498/36433 UL http://hdl.handle.net/10498/36433 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 08-nov-2026